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End-stage respiratory disease 

End-stage respiratory disease
End-stage respiratory disease

Anna Spathis

, Helen E. Davies

, Sara Booth

, and Max Watson

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date: 20 June 2021

The burden of end-stage respiratory disease 2

Disease trajectories 4

Chronic obstructive pulmonary disease 6

Lung cancer 10

Mesothelioma 16

Interstitial lung disease 20

Chest wall and neuromuscular disease 22

Pulmonary hypertension 26

Cystic fibrosis 30

Further reading 32

Respiratory disease is a major public health problem. Advances in available treatments have prolonged the life expectancy for many chronic lung conditions. As survival increases, so does the burden of patient morbidity and the adverse impact on patients’ quality of life. In turn, the demand on healthcare services is intensifying....

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