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Intrathecal drug delivery and neurolytic blocks 

Intrathecal drug delivery and neurolytic blocks
Chapter:
Intrathecal drug delivery and neurolytic blocks
Author(s):

Karen H. Simpson

and Iain Jones

DOI:
10.1093/med/9780199563678.003.0015
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date: 17 January 2021

Intrathecal drug delivery (ITDD) allows drugs to be placed near to central receptors

Drug side-effects may be reduced as small doses are required compared to with systemic administration

External or internal ITDD systems are available

ITDD requires careful patient selection and preparation

Opioids, local anaesthetics, and clonidine are the most commonly used intrathecal drugs; ziconotide can be used as first line treatment...

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