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Michael I. Bennett

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date: 24 September 2021

Opioid receptor structure and function can be altered in neuropathic pain states, leading to reduced sensitivity to opioids

Opioids were thought to be ineffective for neuropathic pain but substantial evidence exists to demonstrate analgesic efficacy, in some cases superior to more commonly used co-analgesics

The most convincing evidence supports use of morphine, oxycodone, and tramadol in neuropathic pain...

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