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Antidepressants and antiepileptics for neuropathic pain 

Antidepressants and antiepileptics for neuropathic pain
Antidepressants and antiepileptics for neuropathic pain

Henry J. McQuay

and Philip Wiffen

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date: 01 August 2021

Antidepressants and antiepileptics are well-established treatments for neuropathic pain

Clinical trial evidence can be limited in both scope of neuropathic pain conditions studied and duration of treatment. This leaves prescribers to extrapolate evidence to other conditions, and without information on longer-term effects

Lack of head-to-head comparisons results in the use of indirect evidence such as NNTs, but the sample size used to derive NNT values is equally important...

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