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Phosphatonins in health and disease 

Phosphatonins in health and disease
Phosphatonins in health and disease

Leslie Thomas

, Mukesh Sinha

, and Rajiv Kumar

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date: 10 August 2020

The model of phosphorus homeostasis has evolved significantly in the past few years and will improve further as new insights are made. The discovery of phosphatonin peptides marks an important milestone in our understanding of the greater scheme of Pi metabolism. Further elucidation of the complex regulatory elements of phosphorus balance may lead to novel therapies for those afflicted with derangements of phosphorus handling, including those with advanced CKD and ESRD.

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