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Clinical features of diabetic peripheral and autonomic neuropathies 

Clinical features of diabetic peripheral and autonomic neuropathies
Clinical features of diabetic peripheral and autonomic neuropathies

Solomon Tesfaye

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date: 27 July 2021

Diabetic polyneuropathy encompasses a number of neuropathic syndromes, the commonest of which is chronic diabetic peripheral neuropathy (DPN).

DPN is associated with significant morbidity and mortality.

Clinical assessment must include a careful history, inquiring about sensory, autonomic, and motor symptoms.

Other possible causes for neuropathy should be excluded.

Peripheral neurological examination should include: inspection of the feet and legs, assessment of sensory modalities including the 10 g monofilament test and examination of ankle and knee reflexes.

Finally footwear should be inspected for poor fit, abnormal wear, and internal pressure areas or foreign bodies.

Cardiac autonomic neuropathy is a serious complication of diabetes that can result in sudden death.

Diabetic autonomic neuropathy has many manifestations.

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