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Inflammatory connective tissue disease 

Inflammatory connective tissue disease
Chapter:
Inflammatory connective tissue disease
Author(s):

Catherine Swales

DOI:
10.1093/med/9780199550647.003.010005
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date: 07 December 2019

Systemic lupus erythematosus (SLE) is the commonest multisystem connective tissue disease

All patients with SLE are antinuclear antibody (ANA) positive, but not all ANA-positive patients have SLE

Renal lupus carries a high mortality and requires aggressive immunosuppression

Dermatomyositis may be associated with malignancy in the elderly

The vasculitides are classified according to vessel size and ANCA (antineutrophil cytoplasmic antibody) profile

Therapy for vasculitis includes corticosteroids, steroid-sparing agents, and cytotoxics.

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