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Sandeep Bawa

, Paul Wordsworth

, and Inoshi Atukorala

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date: 17 May 2022

Spondyloarthropathies are related conditions typically associated with axial skeletal involvement, absence of rheumatoid factor, familial clustering, and a variable positive association with HLA-B27

Ankylosing spondylitis is the prototype with sacroiliac joint involvement being a prerequisite for diagnosis

Diagnosis is frequently delayed for several years but the use of magnetic resonance imaging to detect sacroiliitis greatly facilitates the establishment of an early diagnosis

Psoriatic arthritis, reactive arthritis, and enteropathic arthritis have prominent peripheral joint involvement with variable degrees of spinal involvement

Non-steroidal anti-inflammatory drugs and physical therapy are the cornerstones of management but slow-acting disease-modifying antirheumatic drugs only have a role in peripheral arthritis

Anti-tumour necrosis factor biologic agents have revolutionized the treatment of the spondyloarthropathies.

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