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Prevention of thrombosis in orthopaedic surgery 

Prevention of thrombosis in orthopaedic surgery
Chapter:
Prevention of thrombosis in orthopaedic surgery
Author(s):

David Warwick

DOI:
10.1093/med/9780199550647.003.0006
Page of

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date: 13 December 2019

The risk–benefit of thromboprophylaxis in orthopaedic surgery remains unclear

Some conditions, such as major trauma, carry a much higher risk than others, such as routine knee replacement

Some patients appear to be genetically more predisposed than others

In trials of efficacy of thromboembolism, the use of deep vein thrombosis as a surrogate endpoint for death from a pulmonary embolus may not be completely reliable

There is a variety of mechanical and chemical methods available, each of which has real and potential advantages as well as real and potential dangers

Even the length of time that a patient is at risk after major surgery is unclear

Clinicians should adhere to guidelines where possible.

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