Show Summary Details
Page of

Primary Prevention of Coronary Heart Disease 

Primary Prevention of Coronary Heart Disease
Chapter:
Primary Prevention of Coronary Heart Disease
Author(s):

Richard Hobbs

DOI:
10.1093/med/9780199544769.003.0002
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2022. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 16 May 2022

Coronary heart disease (CHD) is the leading cause of death and disability in the world

The evidence base for the causes of CHD and for the interventions which reduce CHD risk is huge

Since CHD is multi-factorial, risk factors tend to co-exist in many patients, and are multiplicative in their influence on overall risk, making identifying people at highest risk clinically difficult

CHD risk scores have been developed, based on observed CHD rates amongst well-phenotyped patient cohorts followed up over years. These express absolute risk over a defined period and are the most practical method for determining which people have the most to gain from treatment interventions

Evidence-based interventions include smoking cessation, lifestyle modification in terms of diet and exercise, anti-hypertensives for elevated blood pressure, and ‘statins’ for hyperlipidaemia

Clinical guidelines for CHD prevention provide recommendations on specific targets for blood pressure and lipid-lowering therapy.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.