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Older Age and HIV 

Older Age and HIV
Older Age and HIV

Karl Goodkin

, David M. Stoff

, Dilip V. Jeste

, and Maria J. Marquine

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date: 13 July 2020

This chapter addresses the growing problem of aging and HIV infection throughout the world. Emphasis is placed on conceptualization such as the development of phenotypes within the population of older persons with HIV. The phenotypes include (1) disability, (2) frailty/vulnerability, (3) comorbid conditions, (4) cognitive aging, (5) premature or accelerated aging, and (6) successful aging. Older age and illness progression is addressed with respect to frailty or vulnerability to progression and the development of a dysfunctional, disabled status in activities of daily living. The issue of older age and HIV-associated neurocognitive disorder is discussed, and the research related to pattern of cognitive impairment, including dementia, is reviewed. The chapter also differentiates characteristics of accelerated aging from characteristics of successful aging. Integration of gerontology with HIV medicine and HIV psychiatry can be accomplished through focusing future study on optimization of functional status and quality of life in aging with HIV.

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