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Neuropsychological Evaluation for Persons with HIV and AIDS 

Neuropsychological Evaluation for Persons with HIV and AIDS
Neuropsychological Evaluation for Persons with HIV and AIDS

Bibilola D. Oladeji

, and Kevin R. Robertson

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date: 07 July 2020

With recent developments in the classification and definitions for HIV-associated neurocognitive disorders (HAND), neuropsychological assessments have become central to the diagnostic process. The pattern and manifestation of neurocognitive dysfunction associated with HIV have changed since the introduction of effective antiretroviral medications and their increasingly widespread use. Prior to the introduction of antiretroviral therapy, severe cognitive disorder presenting as HIV-associated dementia (HAD) was a common manifestation of HIV-associated neurocognitive disorders. In more recent times, however, milder forms of neurocognitive impairment have become more common, often being asymptomatic and difficult to recognize without formal neuropsychological testing. Hence, recognizing individuals at most risk for cognitive decline through neuropsychological testing will offer opportunities for developing targeted interventions that could delay disease progression and improve individual functioning and quality of life.

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