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Respiratory Functional Anatomy and Pharmacology 

Respiratory Functional Anatomy and Pharmacology
Chapter:
Respiratory Functional Anatomy and Pharmacology
Author(s):

Omonele Ohen Nwokolo

and Tolutope Coker

DOI:
10.1093/med/9780199381623.003.0024
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date: 20 August 2019

This chapter reviews the anatomical components of the airway and upper respiratory system, including blood flow patterns and anatomic physiology and their implications for therapy. Respiratory anatomy and pharmacology and physiology are discussed. This includes a review of the muscles of respiration and their function during active inspiration and passive and forced expiration. The diaphragm is highlighted as the principal muscle in respiratory anatomy, and there is a focus on the pharmacology necessary to treat the most common respiratory ailments such as bronchospasm, asthma, and COPD. These pharmacological interventions include bronchodilators and their subclasses and anti-inflammatory medications and their subtypes. There is a description of the function, mechanism of action, indications, and in some cases the dose of the medication prototypes. On completion of this chapter, the goal is to understand the basics of muscles involved in respiratory mechanics and to appropriately treat when these mechanics are hindered.

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