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Steroids for Bell’s Palsy 

Steroids for Bell’s Palsy
Chapter:
Steroids for Bell’s Palsy
Author(s):

Benjamin N. Blond

DOI:
10.1093/med/9780199377527.003.0007
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date: 15 September 2019

This chapter provides a summary of a landmark study in neuroinfectious disease. Does early therapy with prednisolone or acyclovir improve complete recovery from Bell’s palsy? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. Researchers demonstrated that corticosteroid therapy within 72 hours of symptom onset is effective in increasing the rate of complete facial nerve function recovery, but the study did not show more rapid recovery with acyclovir versus placebo, casting doubt on antiviral therapy. The chapter briefly reviews other relevant studies and information, and concludes with a relevant clinical case.

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