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Carotid Endarterectomy for Asymptomatic Carotid Stenosis: The ACAS Trial 

Carotid Endarterectomy for Asymptomatic Carotid Stenosis: The ACAS Trial
Chapter:
Carotid Endarterectomy for Asymptomatic Carotid Stenosis: The ACAS Trial
Author(s):

Daniel C. Brooks

DOI:
10.1093/med/9780199377527.003.0042
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date: 22 September 2019

This chapter provides a summary of a landmark study in vascular neurology. For patients with asymptomatic carotid stenosis, does carotid endarterectomy reduce the risk of ischemic stroke compared with medical therapy alone? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. Selected patients with asymptomatic carotid artery stenosis of ≥60% reduction in diameter have a reduced 5-year risk of ipsilateral stroke with endarterectomy plus medical management versus medical management alone. Surgery is associated with perioperative risk, however. The chapter briefly reviews other relevant studies and information, and concludes with a relevant clinical case.

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