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Carotid Endarterectomy for Symptomatic High-Grade Carotid Stenosis: The NASCET Trial, Part I 

Carotid Endarterectomy for Symptomatic High-Grade Carotid Stenosis: The NASCET Trial, Part I
Chapter:
Carotid Endarterectomy for Symptomatic High-Grade Carotid Stenosis: The NASCET Trial, Part I
Author(s):

Hardik P. Amin

DOI:
10.1093/med/9780199377527.003.0040
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date: 22 September 2019

This chapter provides a summary of a landmark study in vascular neurology. Does carotid endarterectomy reduce the risk of stroke or death in patients with symptomatic high-grade carotid stenosis? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The study was the first large North American randomized controlled trial to demonstrate the benefits of carotid endarterectomy for patients with 70%–99% carotid stenosis and to describe perioperative risk among the chosen patient population. The chapter briefly reviews other relevant studies and information and discusses implications.

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