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Endovascular Therapy for Acute Ischemic Stroke, Part IV (Clinical Trial Success): The MR CLEAN Trial 

Endovascular Therapy for Acute Ischemic Stroke, Part IV (Clinical Trial Success): The MR CLEAN Trial
Chapter:
Endovascular Therapy for Acute Ischemic Stroke, Part IV (Clinical Trial Success): The MR CLEAN Trial
Author(s):

Matthew D. Kalp

and David Y. Hwang

DOI:
10.1093/med/9780199377527.003.0039
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date: 18 September 2019

This chapter provides a summary of a landmark study in vascular neurology. Do patients with an acute ischemic stroke due to a proximal occlusion of the anterior cerebral circulation benefit from intra-arterial treatment within 6 hours of symptom onset? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The study was the first in a number of recent research studies that have demonstrated that intra-arterial treatment within 6 hours of acute ischemic stroke caused by proximal intracranial occlusion of the anterior circulation improves outcome. The chapter briefly reviews other relevant studies and information, and concludes with a relevant clinical case.

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