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IVIG versus Plasma Exchange for Guillain-Barré Syndrome 

IVIG versus Plasma Exchange for Guillain-Barré Syndrome
Chapter:
IVIG versus Plasma Exchange for Guillain-Barré Syndrome
Author(s):

Irene Hwa Yang

DOI:
10.1093/med/9780199377527.003.0022
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date: 15 September 2019

This chapter provides a summary of a landmark study in neuromuscular disease. Is intravenous immunoglobulin equally effective or superior to plasma exchange for treatment of Guillain-Barré Syndrome? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. In patients with Guillain-Barré syndrome, treatment with plasma exchange or IVIG is equally efficacious. Combination treatment of plasma exchange immediately followed by IVIG has not been established as superior to monotherapy. The chapter briefly reviews other relevant studies and information, and concludes with a relevant clinical case.

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