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Fingolimod for Relapsing Multiple Sclerosis: The TRANSFORMS Trial 

Fingolimod for Relapsing Multiple Sclerosis: The TRANSFORMS Trial
Chapter:
Fingolimod for Relapsing Multiple Sclerosis: The TRANSFORMS Trial
Author(s):

Mary A. Bailey

DOI:
10.1093/med/9780199377527.003.0015
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date: 19 September 2019

This chapter provides a summary of a landmark study in multiple sclerosis. Does oral fingolimod or intramuscular interferon have superior efficacy in treating relapsing multiple sclerosis? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. Researchers found that in patients with relapsing-remitting multiple sclerosis, oral fingolimod is superior to intramuscular interferon beta-1a with regard to relapse rates and MRI outcomes. The chapter briefly reviews other relevant studies and information, and concludes with a relevant clinical case.

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