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Glatiramer Acetate for Clinically Isolated Syndrome: The PreCISe Trial 

Glatiramer Acetate for Clinically Isolated Syndrome: The PreCISe Trial
Chapter:
Glatiramer Acetate for Clinically Isolated Syndrome: The PreCISe Trial
Author(s):

Sarah A. Mulukutla

DOI:
10.1093/med/9780199377527.003.0013
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date: 22 September 2019

This chapter provides a summary of a landmark study in multiple sclerosis. Can early treatment with glatiramer acetate reduce the risk of conversion to multiple sclerosis in patients with clinically isolated syndrome? Starting with that question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The study demonstrated that early treatment with glatiramer acetate in patients with a clinically isolated syndrome significantly delays time to onset of clinically definite multiple sclerosis. The chapter briefly reviews other relevant studies and information, and concludes with a relevant clinical case.

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