Show Summary Details
Page of

Alcoholic Liver Diseasea 

Alcoholic Liver Diseasea
Chapter:
Alcoholic Liver Diseasea
Author(s):

Robert C. Huebert

and Vijay H. Shah

DOI:
10.1093/med/9780199373338.003.0030
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 04 December 2020

Alcoholic liver disease is a major cause of morbidity and mortality in the United States. Alcohol is implicated in more than 50% of liver-related deaths in the United States, and complications of alcoholism contribute to a quarter of a million deaths annually. Also, alcoholic liver disease is a major health care cost expenditure, accounting for nearly $3 billion annually. The clinical spectrum of alcoholic liver disease includes fatty liver, alcoholic hepatitis, and alcoholic cirrhosis. Fatty liver develops in response to short periods (days) of alcohol abuse. It is generally asymptomatic and reversible with abstinence. More advanced liver injury usually requires prolonged alcohol abuse over a period of years. Of note, the majority of people who abuse alcohol for extended periods do not develop more advanced lesions of alcoholic liver disease. However, alcoholic hepatitis or alcoholic cirrhosis (or both) develops in about 20% of these people.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.