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Inflammatory Bowel Disease: Extraintestinal Manifestations and Colorectal Cancer 

Inflammatory Bowel Disease: Extraintestinal Manifestations and Colorectal Cancer
Inflammatory Bowel Disease: Extraintestinal Manifestations and Colorectal Cancer

Laura E. Raffals

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date: 02 April 2020

Ulcerative colitis (UC) and Crohn disease (CD) are inflammatory disorders that affect the gastrointestinal tract. However, these diseases are systemic disorders that may involve other organ systems. Extraintestinal manifestations can affect any organ system, and while in many cases these symptoms are believed to be a result of the underlying intestinal inflammation, some extraintestinal manifestations are independent of the luminal disease course. Extraintestinal manifestations may precede the diagnosis of inflammatory bowel disease (IBD). Many patients experiencing extraintestinal manifestations have colonic disease, and in individuals with 1 extraintestinal manifestation, another extraintestinal symptom is more likely to develop.

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