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Peripheral Nerve Stimulation 

Peripheral Nerve Stimulation
Peripheral Nerve Stimulation

Lucas Campos

, and Jason E. Pope

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date: 22 January 2021

Neuromodulation is the process of altering nerve impulses through electrical or chemical mechanisms. Peripheral nerve stimulation (PNS) is one of the most diverse and rapidly expanding areas of neuromodulation. The goal of this chapter is to increase awareness of the theory, basic science, and ongoing clinical indications of PNS. The use of PNS is a natural outgrowth from traditional methods of using neurostimulation in the spinal canal. Various disease states are theoretically amenable to PNS, including headache disorders such as migraine and cluster headache. Significant and specific risks, safety concerns, and adverse events are possible with PNS, particularly without a focus on prevention.

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