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Psychopharmacology of Autism Spectrum Disorder 

Psychopharmacology of Autism Spectrum Disorder
Psychopharmacology of Autism Spectrum Disorder

James T. McCracken

and Michael Gandal

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date: 24 May 2022

The use of medications in the treatment of autism spectrum disorder (ASD) has been rapidly incorporated into clinical practice, although their role continues to be adjunctive, not primary treatments for ASD per se. Evidence supporting the use of medications in ASD has grown considerably. Clinicians need to be familiar with the types of behaviors that may provide an indication for medication treatment, which agents are best supported, and how to apply these treatments in a safe and effective manner. This chapter serves as a comprehensive review of the use of psychopharmacologic treatments in ASD for clinicians in training and those with less background in the care of individuals with ASD, focusing on treatments with an acceptable evidence base, and providing clinical guidance for prescribing, monitoring effectiveness, and ensuring safety. Where relevant, additional information on emerging research findings and the molecular basis of drug action in ASD is included.

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