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Non-Opioid Medications 

Non-Opioid Medications
Chapter:
Non-Opioid Medications
Author(s):

Adam Canter

, Vijay Babu

, and Karina Gritsenko

DOI:
10.1093/med/9780199349302.003.0006
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date: 18 October 2019

This chapter examines the role of non-opioid medications in acute on chronic pain management for the hospitalized patient. Such medications include nonsteroidal anti-inflammatory drugs, antidepressants, local anesthetics, membrane stabilizers, and ketamine. Non-opioid medications may have a significant opioid-sparing effect in the hospital setting. Distinguishing between neuropathic and somatic pain, and weighing the risks and benefits with regard to the mechanism of action as well as the side-effect profile of each non-opioid agent used are essential for safe and effective pain control. A delicate balance needs to be maintained for each individual patient, based on history, physical exam, comorbidities, medication profile, and specific acute on chronic pain needs.

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