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Tumors of the Central Nervous System 

Tumors of the Central Nervous System
Tumors of the Central Nervous System

Katherine E. Warren

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date: 15 April 2021

Tumors of the central nervous system (CNS) are the most common solid tumors of childhood, with approximately 4,000 children diagnosed with a malignant or nonmalignant CNS tumor each year. Pediatric CNS tumors are a heterogeneous group of diseases, varying in their histology, location, biology, prognosis and treatment approach. Location of the tumor is important because it defines the area of the brain involved and the subsequent function affected. Modalities for treatment of CNS tumors include surgery, radiation and chemotherapy. Almost all survivors of pediatric CNS tumors will have long-term effects from the tumor and its treatment. Web resources, such as the CureSearch website ( and the Children’s Oncology Group’s Long-Term Follow-up Guidelines are now available as excellent resources to clinicians and parents alike to provide answers to many of the questions that arise regarding late effects in brain tumor survivors.

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