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Edith O’Neil-Page

, Paula R. Anderson

, and Grace E. Dean

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date: 04 December 2021

This chapter provides an overview of fatigue as it spans the illness trajectory and end-of-life experience for patients with chronic progressive disease. While fatigue is a complex phenomenon that has been widely studied, there is still no universally accepted definition. Individuals with cancer and many other chronic, progressive diseases continue to experience fatigue and its costs, not only in the economic sense but also in its physical, emotional, and psychological impact on life. Cancer-related fatigue is a serious problem that interferes with physical, psychological, emotional, social, and economic functions. The need for healthcare providers to recognize and identify symptoms and explore management strategies is crucial to the lessening of human suffering.

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