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Botanical and Mycological Medicine in Integrative Oncology 

Botanical and Mycological Medicine in Integrative Oncology
Chapter:
Botanical and Mycological Medicine in Integrative Oncology
Author(s):

Leanna J. Standish

, Lise N. Alschuler

, Morgan Weaver

, and M. Nezami

DOI:
10.1093/med/9780199329724.003.0007
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date: 17 October 2019

Chapter 7 discusses botanical and mycological medicine in integrative oncology, including how many of the best chemotherapy drugs originally came from plants (paclitaxel, vincristine, vinblastine, vinorelbine, camptothecin, podophyllin), that there are still antineoplastic and immunomodulatory plant and fungal medicines yet to be discovered, that some ancient Traditional Chinese Medicine (TCM) combination therapies have been shown to improve the response rates to chemotherapy in people with various cancers such as pancreatic and colon cancer, that the botanicals/botanically derived compounds with the highest level of preclinical/clinical evidence as anticancer or immunomodulatory agents include Allium sativum (garlic), curcumin (Curcuma longa), Camellia sinensis (green tea), resveratrol (Polygonum cuspidatum), artemisinin (Artemisia annua), Viscum spp. (mistletoe), quercetin, bromelain, Silybum marianum (milk thistle), Astragalus membranaceous (astragalus), Withania somnifera (ashwagandha), and mushrooms Trametes versicolor (turkey tail), Ganoderma lucidum (reishi), Lentinus edodes (shiitake), and Grifola frondosa (maitake), and the critical need for clinical research trials of single botanical agents as well as combination botanical treatments.

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