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Psychiatric Presentations Associated with Organ Failure and Systemic Illness 

Psychiatric Presentations Associated with Organ Failure and Systemic Illness
Psychiatric Presentations Associated with Organ Failure and Systemic Illness

Pierre N. Azzam

, Priya Gopalan

, Abhishek Jain

, Francis E. Lotrich

, and Kevin R. Patterson

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date: 22 September 2020

The interface between medicine and psychiatry hosts a complex interplay between psychological and physiological processes, requiring vigilance on the part of the general hospital psychiatrist. Cardiac, pulmonary, hepatic, metabolic, autoimmune, and infectious disorders present often with psychiatric comorbidities, which in turn have implications on quality of life, adherence, and treatment course. Additionally, impaired organ function may influence use of psychotropic medications, whether by dose adjustment, slower titration, or avoidance altogether. Knowledge of such areas—including the effects of coronary artery disease and congestive heart failure on depression, psychiatric and cognitive manifestations of hepatic encephalopathy, and medication management in the setting of renal impairment, liver disease, or HIV infection—enables the psychiatrist to provide comprehensive care to medically ill patients.

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