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Genetic and Hereditary Considerations for Arrhythmias in Women 

Genetic and Hereditary Considerations for Arrhythmias in Women
Chapter:
Genetic and Hereditary Considerations for Arrhythmias in Women
Author(s):

Ohad Ziv

and Elizabeth S. Kaufman

DOI:
10.1093/med/9780199321971.003.0003
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date: 21 October 2019

As the molecular basis for cardiac electrophysiology has become more clearly understood, the importance of heritable factors in the clinical manifestation of cardiac arrhythmias has become more apparent. The role of heritable factors may be subtle, as in atrial fibrillation, or obvious, as in short QT syndrome and long QT syndrome. It is also apparent that sex hormones exert an influence on cardiac electrophysiology. Cardiac myocytes have been found to express receptors to estrogen, progesterone, and testosterone. This chapter focuses on the intersection of the influence of heritable effects and sex effects on cardiac arrhythmias.

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