Show Summary Details
Page of

Integrative Management of Rheumatoid Arthritis 

Integrative Management of Rheumatoid Arthritis
Chapter:
Integrative Management of Rheumatoid Arthritis
Author(s):

Nisha J. Manek

DOI:
10.1093/med/9780199315246.003.0046
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 19 June 2019

Integrative management augments the clinical outcomes for rheumatoid arthritis (RA) which have dramatically improved owing to multiple factors including earlier diagnosis, biologic therapeutics and aggressive treat to a target strategy. Integrative management can help ameliorate periodontitis, an environmental factor that increases the expression of RA-specific anti-citrullinated protein auto-antibodies. The discovery of novel omega-3 derived lipid mediators, termed resolvins and protectins, has been a major breakthrough for understanding the processes involved in resolution of inflammation and reduction of pain. Turmeric (Curcuma longa) extracts have been shown to have potent antiarthritic effects via pleotropic activities emanating from its ability to modulate numerous signaling molecules such as nuclear factor ?B (NF-?B) and pro-inflammatory cytokines. The cholinergic anti-inflammatory pathway is a neural mechanism that suppresses the innate inflammatory response and this knowledge enables consideration of the neurological basis of integrative therapies such as meditation and acupuncture in treatment of RA. Heart rate variability may be a novel predictor of response to biologic therapies in patients with RA and emphasizes the autonomic influence of RA expression. Data in physics show that directed human intention, or information, can influence whole living systems in a specific and individual direction and this emerging paradigm holds promise in the delivery of personalized medicine for RA.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.