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Integrative Management of Rheumatoid Arthritis 

Integrative Management of Rheumatoid Arthritis
Integrative Management of Rheumatoid Arthritis

Nisha J. Manek

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date: 16 September 2021

Integrative management augments the clinical outcomes for rheumatoid arthritis (RA) which have dramatically improved owing to multiple factors including earlier diagnosis, biologic therapeutics and aggressive treat to a target strategy. Integrative management can help ameliorate periodontitis, an environmental factor that increases the expression of RA-specific anti-citrullinated protein auto-antibodies. The discovery of novel omega-3 derived lipid mediators, termed resolvins and protectins, has been a major breakthrough for understanding the processes involved in resolution of inflammation and reduction of pain. Turmeric (Curcuma longa) extracts have been shown to have potent antiarthritic effects via pleotropic activities emanating from its ability to modulate numerous signaling molecules such as nuclear factor ?B (NF-?B) and pro-inflammatory cytokines. The cholinergic anti-inflammatory pathway is a neural mechanism that suppresses the innate inflammatory response and this knowledge enables consideration of the neurological basis of integrative therapies such as meditation and acupuncture in treatment of RA. Heart rate variability may be a novel predictor of response to biologic therapies in patients with RA and emphasizes the autonomic influence of RA expression. Data in physics show that directed human intention, or information, can influence whole living systems in a specific and individual direction and this emerging paradigm holds promise in the delivery of personalized medicine for RA.

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