Contents

Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Show Summary Details
Page of

Acute myeloid leukaemia 

Acute myeloid leukaemia
Chapter:
Acute myeloid leukaemia
DOI:
10.1093/med/9780199299676.003.27
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 14 October 2019

Epidemiology 406

Aetiology 407

Clinical presentation 408

Investigations 409

Diagnosis 409

Classification 410

Risk stratification 413

Treatment 414

Prognosis 418

The future 418

Acute myeloid leukaemia (AML) comprises a group of clonal disorders caused by maturation arrest leading to proliferation of abnormal myeloid precursor cells. However, this definition incorporates a wide and heterogenous group of leukaemias (see Classification). The prognosis of paediatric AML was very poor until the introduction of intensive chemotherapy protocols in the 1980s, but has now improved greatly although survival rates still lag behind those for ALL....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.