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Biology and genetics of childhood cancer 

Biology and genetics of childhood cancer
Chapter:
Biology and genetics of childhood cancer
DOI:
10.1093/med/9780199299676.003.02
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date: 20 October 2019

What is cancer? 22

What causes cancer? 22

Oncogenes 23

Tumour suppressor genes 24

DNA repair genes 25

Non-random, somatic genetic abnormalities in childhood cancers 26

Heritable genetic abnormalities associated with childhood cancers 30

Targeted treatments for molecular defects in childhood cancers 34

Practical considerations ...

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