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Opioid rotation 

Opioid rotation
Opioid rotation

Janet R. Hardy

, Columba Quigley

, and Joy R. Ross

Page of

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date: 17 September 2021

Chapter 20 discusses a practice that is becoming increasingly common, and is generally known as ‘opioid rotation’, and addresses that the most common reason for opioid rotation is opioid-related toxicity often associated with suboptimal pain control, as well as other practical issues which often apply, such as cost, drug volume (the relatively poor solubility of some drugs renders it difficult to give large doses by subcutaneous infusion), drug availability, convenience, familiarity, and experience, together with physician and patient preference.

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