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Paul Glare

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date: 24 September 2021

Chapter 8 discusses Dextropropoxyphene (DPP), known as propoxyphene in the USA, which is a synthetic weak opioid analgesic of the diphenylpropylamine class, which is derived from the synthetic strong opioid methadone. It is an increasingly controversial drug. DPP is a base, with a pKa of 6.3. It has an active metabolite norpropoxyphene (NPP) which is a non-opioid. The chapter also covers viewpoints of both those who advocate and oppose its use.

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