Contents

Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Show Summary Details
Page of

Premature sexual maturation 

Premature sexual maturation
Chapter:
Premature sexual maturation
Author(s):

Jean-Claude Carel

and Juliane Léger

DOI:
10.1093/med/9780199235292.003.7112
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2020. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 10 August 2020

Premature sexual maturation is a frequent cause for referral in paediatric endocrinology. Although clinical evaluation will suffice to reassure the patient and family in a majority of cases, premature sexual maturation can reveal severe conditions and need a thorough evaluation to identify its cause and potential for progression, in order to propose an appropriate treatment (1). Although the use of long-acting GnRH agonists has revolutionized the treatment of central precocious puberty, questions remain regarding their optimal use (2). One of the main ongoing controversial issues in the area is the definition of normal pubertal development and there is a need for longitudinal assessments of normally developing children in the various areas of the world and of a better understanding of the factors affecting normal pubertal development to improve the recognition and proper management of premature sexual maturation.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.