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Adrenocortical cancer 

Adrenocortical cancer
Chapter:
Adrenocortical cancer
Author(s):

Rossella Libè

, Lionel Groussin

, Xavier Bertagna

, and Jérôme Bertherat

DOI:
10.1093/med/9780199235292.003.0542
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date: 13 November 2019

Adrenocortical cancer (ACC) is among the most aggressive endocrine tumours with an overall very poor prognosis. Morbidity and mortality can be secondary to steroid hormone excess and/or tumour growth and metastases. This potentially poor outcome justifies the importance of considering malignancy in the man-agement of an adrenal mass. The diagnosis of malignancy in a patient with an adrenal tumour relies on careful investigations of clinical, biological, and imaging features before surgery and path-ological examination after tumour removal. Appropriate man-agement and follow-up by an expert multidisciplinary team is important to improve prognosis and to progress in these rare neoplasms.

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