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Parathyroid anatomy, hormone synthesis, secretion, action, and receptors 

Parathyroid anatomy, hormone synthesis, secretion, action, and receptors
Chapter:
Parathyroid anatomy, hormone synthesis, secretion, action, and receptors
Author(s):

Geoffrey N. Hendy

and David Goltzman

DOI:
10.1093/med/9780199235292.003.0404
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date: 23 May 2022

Humans have two pairs of parathyroid glands lying in the anterior cervical region. The fetal parathyroid glands begin developing at 5 weeks from the third and fourth pharyngeal pouches. The third pharyngeal pouch, which contains tissue that will become the thymus and parathyroid, migrates downward and gives rise to the two inferior parathyroid glands normally located at the lower poles of the thyroid. The fourth pharyngeal pouch does not migrate and gives rise to the two upper parathyroid glands, which normally are attached to the upper poles of the thyroid (1).

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