- Part 1 Principles of international endocrine practice
- Part 2 Pituitary and hypothalamic diseases
- Part 3 The thyroid
- 3.1 Evaluation of the thyroid patient
- 3.2 Aetiology of thyroid disorders
- 3.3 Thyrotoxicosis and related disorders
- 3.3.1 Clinical assessment and systemic manifestations of thyrotoxicosis
- 3.3.2 Thyrotoxic periodic paralysis
- 3.3.3 Thyrotoxic storm
- 3.3.4 Subclinical hyperthyroidism
- 3.3.5 Causes and laboratory investigations of thyrotoxicosis
- 3.3.6 Antithyroid drug treatment for thyrotoxicosis
- 3.3.7 Radio-iodine treatment of hyperthyroidism
- 3.3.8 Surgery for thyrotoxicosis
- 3.3.9 Management of Graves’ hyperthyroidism
- 3.3.10 Graves’ ophthalmopathy and dermopathy
- 3.3.11 Management of toxic multinodular goitre and toxic adenoma
- 3.3.12 Management of thyrotoxicosis without hyperthyroidism
- 3.4 Hypothyroidism and pregnancy- and growth-related thyroid disorders
- 3.5 Thyroid lumps
- Part 4 Parathyroid, calcium, and bone metabolism
- Part 5 The adrenal gland and endocrine hypertension
- Part 6 Neuroendocrine tumours and genetic disorders
- Part 7 Growth and development during childhood
- Part 8 Female endocrinology and pregnancy
- Part 9 Male hypogonadism and infertility
- Part 10 Endocrinology of ageing and systemic disease
- Part 11 Endocrinology of cancer
- Part 12 Obesity, lipids, and metabolic disorders
- Part 13 Diabetes mellitus
Subclinical hyperthyroidism
- Chapter:
- Subclinical hyperthyroidism
- Author(s):
Jayne A. Franklyn
- DOI:
- 10.1093/med/9780199235292.003.3177
Subclinical hyperthyroidism is defined biochemically as the association of a low serum thyroid-stimulating hormone (TSH) value with normal circulating concentrations of free thyroxine (T4) and free triiodothyronine (T3). The biochemical diagnosis of subclinical hyperthyroidism is dependent upon the use of sensitive assays for TSH able to distinguish normal values found in euthyroid people from reduced values, so our understanding of this topic has accumulated in recent years since such assays became widely available. An expert panel has recently classified patients with subclinical hyperthyroidism into two groups (1): (1) those with low but detectable serum TSH (0.1–0.4 mU/l) and (2) those with undetectable serum TSH (<0.1 mU/l) reflecting the fact that studies of this condition largely divide people into these categories and that the likely consequences reflect the biochemical severity of the condition.
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- Part 1 Principles of international endocrine practice
- Part 2 Pituitary and hypothalamic diseases
- Part 3 The thyroid
- 3.1 Evaluation of the thyroid patient
- 3.2 Aetiology of thyroid disorders
- 3.3 Thyrotoxicosis and related disorders
- 3.3.1 Clinical assessment and systemic manifestations of thyrotoxicosis
- 3.3.2 Thyrotoxic periodic paralysis
- 3.3.3 Thyrotoxic storm
- 3.3.4 Subclinical hyperthyroidism
- 3.3.5 Causes and laboratory investigations of thyrotoxicosis
- 3.3.6 Antithyroid drug treatment for thyrotoxicosis
- 3.3.7 Radio-iodine treatment of hyperthyroidism
- 3.3.8 Surgery for thyrotoxicosis
- 3.3.9 Management of Graves’ hyperthyroidism
- 3.3.10 Graves’ ophthalmopathy and dermopathy
- 3.3.11 Management of toxic multinodular goitre and toxic adenoma
- 3.3.12 Management of thyrotoxicosis without hyperthyroidism
- 3.4 Hypothyroidism and pregnancy- and growth-related thyroid disorders
- 3.5 Thyroid lumps
- Part 4 Parathyroid, calcium, and bone metabolism
- Part 5 The adrenal gland and endocrine hypertension
- Part 6 Neuroendocrine tumours and genetic disorders
- Part 7 Growth and development during childhood
- Part 8 Female endocrinology and pregnancy
- Part 9 Male hypogonadism and infertility
- Part 10 Endocrinology of ageing and systemic disease
- Part 11 Endocrinology of cancer
- Part 12 Obesity, lipids, and metabolic disorders
- Part 13 Diabetes mellitus