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Hypopituitarism: replacement of adrenal, thyroid, and gonadal axes 

Hypopituitarism: replacement of adrenal, thyroid, and gonadal axes
Hypopituitarism: replacement of adrenal, thyroid, and gonadal axes

Trevor A. Howlett

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date: 20 May 2022

Hormone replacement of anterior pituitary hormone deficiency is one of the most frequent clinical interventions in pituitary disease, yet is an area which has rarely been the subject of rigorous scientific evaluation. Even in an era of ‘evidence-based’ medicine, recommendations for patient management are frequently based predominantly on clinical experience, consensus guidelines and occasional retrospective reviews rather than on controlled, prospective clinical trials. Within these limitations, this chapter will attempt to give a balanced view on current best management of adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH) and gonadotropin deficiency.

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