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Pituitary carcinoma 

Pituitary carcinoma
Pituitary carcinoma

John Ayuk

, Christopher J. McCabe

, and Neil J. L. Gittoes

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date: 27 January 2022

Most pituitary adenomas are slow-growing, benign tumours. Some do, however, demonstrate aggressive growth characteristics that include infiltration of the dura, bone, and surrounding tissues. Despite such apparent aggressive features, these invasive adenomas are not considered to be truly malignant. To make a diagnosis of pituitary carcinoma requires the presence of a pituitary tumour associated with central nervous system or systemic metastases. Little is known of the pathogenesis of these tumours and the prognostication of future tumour behaviour through clinical, histopathological, or molecular analyses remains challenging (1).

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