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Diabetic neuropathy 

Diabetic neuropathy
Chapter:
Diabetic neuropathy
Author(s):

Solomon Tesfaye

DOI:
10.1093/med/9780199235292.003.1529
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date: 17 November 2019

Diabetic neuropathy is a major complication of diabetes and a cause of considerable morbidity and mortality (1). Diabetic neuropathy is not a single entity but includes several neuropathic syndromes (Fig. 13.5.4.1). In clinical practice, the commonest presentation of neuropathy is chronic distal symmetrical polyneuropathy, also known as diabetic peripheral neuropathy (DPN). The neuropathic syndromes depicted in Fig. 13.5.4.1 have varied presentations and pathogenesis. This chapter will cover these syndromes although the main focuses will be: (1) DPN, which is the main initiating factor for foot ulceration and a cause of troublesome painful neuropathic symptoms; and (2) autonomic neuropathy.

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