- Part 1 Principles of international endocrine practice
- Part 2 Pituitary and hypothalamic diseases
- Part 3 The thyroid
- Part 4 Parathyroid, calcium, and bone metabolism
- Part 5 The adrenal gland and endocrine hypertension
- Part 6 Neuroendocrine tumours and genetic disorders
- Part 7 Growth and development during childhood
- Part 8 Female endocrinology and pregnancy
- Part 9 Male hypogonadism and infertility
- Part 10 Endocrinology of ageing and systemic disease
- Part 11 Endocrinology of cancer
- Part 12 Obesity, lipids, and metabolic disorders
- Part 13 Diabetes mellitus
- 13.1 Classification and diagnosis of diabetes mellitus
- 13.2 Aetiology and pathogenesis of type 1 diabetes mellitus
- 13.3 Aetiology and pathogenesis of type 2 diabetes mellitus
- 13.4 Management of diabetes mellitus
- 13.5 Microvascular complications
- 13.5.1 Pathogenesis of microvascular disease
- 13.5.2 Diabetic retinopathy
- 13.5.3 Diabetic nephropathy
- 13.5.4 Diabetic neuropathy
- 13.6 Macrovascular diseases and diabetes mellitus
- 13.7 The diabetic foot
- 13.8 Mental health and diabetes mellitus
- 13.9 Organization of diabetes care
- 13.10 Transplantation in Diabetes
- 13.11 Gene therapy in diabetes mellitus
Diabetic neuropathy
- Chapter:
- Diabetic neuropathy
- Author(s):
Solomon Tesfaye
- DOI:
- 10.1093/med/9780199235292.003.1529
Diabetic neuropathy is a major complication of diabetes and a cause of considerable morbidity and mortality (1). Diabetic neuropathy is not a single entity but includes several neuropathic syndromes (Fig. 13.5.4.1). In clinical practice, the commonest presentation of neuropathy is chronic distal symmetrical polyneuropathy, also known as diabetic peripheral neuropathy (DPN). The neuropathic syndromes depicted in Fig. 13.5.4.1 have varied presentations and pathogenesis. This chapter will cover these syndromes although the main focuses will be: (1) DPN, which is the main initiating factor for foot ulceration and a cause of troublesome painful neuropathic symptoms; and (2) autonomic neuropathy.
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- Part 1 Principles of international endocrine practice
- Part 2 Pituitary and hypothalamic diseases
- Part 3 The thyroid
- Part 4 Parathyroid, calcium, and bone metabolism
- Part 5 The adrenal gland and endocrine hypertension
- Part 6 Neuroendocrine tumours and genetic disorders
- Part 7 Growth and development during childhood
- Part 8 Female endocrinology and pregnancy
- Part 9 Male hypogonadism and infertility
- Part 10 Endocrinology of ageing and systemic disease
- Part 11 Endocrinology of cancer
- Part 12 Obesity, lipids, and metabolic disorders
- Part 13 Diabetes mellitus
- 13.1 Classification and diagnosis of diabetes mellitus
- 13.2 Aetiology and pathogenesis of type 1 diabetes mellitus
- 13.3 Aetiology and pathogenesis of type 2 diabetes mellitus
- 13.4 Management of diabetes mellitus
- 13.5 Microvascular complications
- 13.5.1 Pathogenesis of microvascular disease
- 13.5.2 Diabetic retinopathy
- 13.5.3 Diabetic nephropathy
- 13.5.4 Diabetic neuropathy
- 13.6 Macrovascular diseases and diabetes mellitus
- 13.7 The diabetic foot
- 13.8 Mental health and diabetes mellitus
- 13.9 Organization of diabetes care
- 13.10 Transplantation in Diabetes
- 13.11 Gene therapy in diabetes mellitus