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Genetics of type 2 diabetes mellitus 

Genetics of type 2 diabetes mellitus
Genetics of type 2 diabetes mellitus

Niels Grarup

, Torben Hansen

, and Oluf Pedersen

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date: 20 May 2022

For years, it has been well known that genetic factors are crucially important for the development of type 2 diabetes. Despite major efforts in seeking to understand the molecular genetic basis, until a few years ago, only a handful of genes responsible for relatively rare monogenic and syndromic subsets of diabetes were detected, and progress in finding genetic predispositions to common type 2 diabetes was lacking. Even though the unravelling of the molecular pathogenesis of type 2 diabetes is still in its infancy, the last few years have, nevertheless, brought some interesting developments. Box provides a glossary of terms used currently in genetics.

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