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Immunoendocrinopathy syndromes 

Immunoendocrinopathy syndromes
Chapter:
Immunoendocrinopathy syndromes
Author(s):

W. A. Scherbaum

and M. Schott

DOI:
10.1093/med/9780199235292.003.0195
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date: 17 November 2019

Autoimmune endocrinopathies arise from immunological abnormalities, which cause endocrine dysfunction by mimicking hormone action, by blocking the binding of hormones to their receptors, or by autoimmune-mediated destruction of endocrine glands. They include autoimmune polyglandular syndromes type I and type II, syndromes with anti-insulin receptor antibodies, POEMS syndrome (plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) and thymic tumours with associated endocrinopathy. Box 10.2.5.1 gives an overview of the autoimmune endocrinopathies discussed in this chapter.

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