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Juvenile idiopathic arthritis 

Juvenile idiopathic arthritis
Chapter:
Juvenile idiopathic arthritis
DOI:
10.1093/med/9780199229994.003.0010
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date: 31 May 2020

Juvenile idiopathic arthritis: overview 352

Oligoarticular juvenile idiopathic arthritis 358

Rheumatoid factor (RF) negative polyarticular JIA 359

Rheumatoid factor (RF) positive polyarticular JIA 360

Systemic onset JIA 362

Juvenile PsA 364

Long-term studies have shown that juvenile idiopathic arthritis (JIA) is not as benign as previously thought, with approximately 50% of adults suffering from persistent inflammation and disability (Packham, 2002). There has been a shift towards early aggressive treatment to limit inflammation and achieve a normal lifestyle, since there is some evidence for a better long-term prognosis with this approach. The development of drugs such as the anti-cytokine agents for disease resistant to conventional treatment has greatly improved disease management....

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