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Neurological drugs 

Neurological drugs
Chapter:
Neurological drugs
Author(s):

Carl Waldmann

, Neil Soni

, and Andrew Rhodes

DOI:
10.1093/med/9780199229581.003.0013
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date: 09 May 2021

Opioid and non-opioid analgesics in the ICU 206

Sedation management in ICU 208

Muscle relaxants 210

Anticonvulsant drugs 212

Cerebroprotective agents 214

Mannitol and hypertonic saline 216

Opioid analgesic drugs remain the mainstay of pain relief in the Critical Care Unit. Abnormal GI function in the critically sick consequently makes enteral administration undesirable. IV administration remains the mainstay. Pharmacokinetic considerations consequent upon organ dysfunction leading to altered absorption, distribution and metabolism usually play the most important role in the choice of agent....

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