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Biological aspects of dementia 

Biological aspects of dementia
Biological aspects of dementia

Jonathan Waite

, Rowan H. Harwood

, Ian R. Morton

, and David J. Connelly

Page of

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date: 15 April 2021

The ageing brain 366

Structure 366

Histological changes 368

Molecular biology 372

Genetics of dementia 374

Summary 376

Humans are unique in the extent to which the brain changes with age. The process of normal ageing causes changes in appearance that are very similar to those found in Alzheimer's disease, and there is a considerable overlap between the findings in healthy brains and those from people with dementia. Apart from a few reports in other higher primates such as chimpanzees these appearances have never been found in other species....

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