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Principles of opioid titration 

Principles of opioid titration
Chapter:
Principles of opioid titration
Author(s):

Marie Fallon

and Sandra McConnell

DOI:
10.1093/med/9780199218806.003.0006
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date: 30 May 2020

There is great variation in the dose of opioid required by individual patients. Doses must be tailored to the individual’s need and should start low and then be adjusted (titrated) according to response-up or down. Short acting opioids should be used during the initial titration period and then converted to longer acting formulations when the required dose to achieve pain control is reached. Opioids are useful for neuropathic pain. Adjuvants have an important role in controlling some types of pain where opioids give insufficient analgesia or where adverse effects become intolerable.

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