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Other alternative oral opioids 

Other alternative oral opioids
Chapter:
Other alternative oral opioids
Author(s):

Matthew Makin

DOI:
10.1093/med/9780199218806.003.0012
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date: 28 May 2020

Some opioids may have advantages over morphine in specific circumstances because of their pharmacokinetic and pharmacodynamic profiles. The fentanyl analogues may have greatest utility for episodic pain. Theoretical advantages such as NMDA receptor antagonism and inhibition of the re-uptake of biogenic monoamines have not been confirmed as producing better efficacy or tolerability in clinical studies.

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