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David MacVicar

and James Crawshaw

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date: 28 October 2020

The primary tumours that are notorious for metastasizing to bone are lung, breast, prostate, kidney and thyroid tumours, although any tumour can spread to bone apart from the primary brain (glial) tumours. Most bone metastases occur in the axial or proximal appendicular skeleton, but they may also occur in peripheral bones such as those of the hands and feet (e.g. lung tumours, melanoma). Bone metastases are typically multiple, although 7–10% are solitary (e.g. lung tumours, kidney tumours). Imaging plays the central role in the detection of bone metastases, and this chapter will discuss the strengths and weaknesses of the various imaging techniques used to identify such metastases.

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